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Prevalence and complications of nonsurgical hypoparathyroidism in Korea: A nationwide cohort study by Kim, Se Hwa; Rhee, Yumie; Kim, Yoo Mee; Won, Young Jun; Noh, Junghyun; Moon, Hyemi; Lee, Juneyoung; Kim, Sin Gon; Xu, Shang-Zhong is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Prevalence and complications of nonsurgical hypoparathyroidism in Korea: A nationwide cohort study about?
## Objective The risk of complications of nonsurgical hypoparathyroidism in Asia is unclear. We estimated the prevalence and risk of complications in patients with nonsurgical hypoparathyroidism. ## Methods We performed a retrospective cohort study using a nationwide claims database from 2005 to 2016. Among the entire Korean population, we identified 897 patients diagnosed with nonsurgical hypoparathyroidism during 2005–2015. We selected 210 patients with nonsurgical hypoparathyroidism during 2005–2008 who had no complications at baseline and followed them to 2016. Control subjects (n = 2075) were matched using propensity scores based on age, sex, and comorbid disease with a 1:10 ratio and monitored until 2016. ## Results The age-standardized prevalence of nonsurgical hypoparathyroidism was 0.2 cases per 100,000 persons in 2005. During a mean follow-up period of 9.5 years, patients with nonsurgical hypoparathyroidism had a higher risk of cardiovascular disease, especially arrhythmia (hazard ratio [HR], 2.03; 95% confidence interval [CI], 1.11–3.70) and heart failure (HR, 2.43; 95% CI, 1.22–4.83). The risk of vertebral fracture was higher in patients than in controls (HR, 2.27; 95%
Who reads Prevalence and complications of nonsurgical hypoparathyroidism in Korea: A nationwide cohort study?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Kim, Se Hwa; Rhee, Yumie; Kim, Yoo Mee; Won, Young Jun; Noh, Junghyun; Moon, Hyemi; Lee, Juneyoung; Kim, Sin Gon; Xu, Shang-Zhong
- Publisher
- Public Library of Science; San Francisco CA: Public Library of Science; Publons; ScienceOpen; Public Library of Science (PLoS) (ISSN 1932-6203)
- Published
- 2020
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)