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BODIPY-based probes for hypoxic environments by Lizhi Gai; Yanfei Liu; Zhikuan Zhou; Hua Lu; Zijian Guo is a Chemistry article available to read on EtoBox.

What is BODIPY-based probes for hypoxic environments about?

Hypoxic environment is an important feature of solid tumors, which comes from the imbalance of oxygen supply and consumption. Over the past few years, substantial progress has focused on the design of hypoxia probes derived from BODIPY scaffolds. Such probes are of particular interest and are closely related to tumor resistance to various therapies. This review highlights the construction strategies, recognition mechanisms as well as biological imaging applications of various BODIPY-based hypoxia probes. The aim is to inspire novel approaches and innovations for designing fluorescent probes to image hypoxic environments, and promote the development of diagnostics for tumors and hypoxia-responsive anticancer nanomedicines.

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Author

Lizhi Gai; Yanfei Liu; Zhikuan Zhou; Hua Lu; Zijian Guo

Publisher

Elsevier BV

Published

2023

Language

EN

Field

Chemistry (Physical Sciences)