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Withdrawal of Antiseizure Medications – for Whom, When, and How? by Francesco Brigo; Serena Broggi; Simona Lattanzi is a Medicine article available to read on EtoBox.

What is Withdrawal of Antiseizure Medications – for Whom, When, and How? about?

ABSTRACT Introduction Epilepsy is a chronic disorder of the brain characterized by an enduring predisposition to generate epileptic seizures. Most patients can achieve complete seizure control (seizure freedom) with antiseizure medications (ASMs). In some of them, the withdrawal of ASMs can be considered. Guidance is required to identify patients in whom drug discontinuation can be safely attempted and to inform when and how ASM withdrawal can be done. Areas covered In this perspective, the authors discuss the evidence on ASM withdrawal in epilepsy patients who are seizure-free and provide some suggestions on how to do it effectively in clinical practice, minimizing the risk of seizure recurrence. Expert opinion The decision of discontinuing ASMs in epilepsy patients should rely on an accurate estimate of seizure recurrence risk. Whenever possible, such a risk should be assessed on an individual basis. The decision should also consider the psychosocial and personal consequences of seizure relapse. No robust evidence is available on the safest tapering regimen.

Who reads Withdrawal of Antiseizure Medications – for Whom, When, and How??

Author

Francesco Brigo; Serena Broggi; Simona Lattanzi

Publisher

Informa UK Limited

Published

2023

Language

EN

Field

Medicine (Health Sciences)