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Development of an open-source measurement system to assess the areal bone mineral density of the proximal femur from clinical CT images by Keisuke Uemura; Yoshito Otake; Masaki Takao; Hiroki Makino; Mazen Soufi; Makoto Iwasa; Nobuhiko Sugano; Yoshinobu Sato is a Medicine article available to read on EtoBox.

What is Development of an open-source measurement system to assess the areal bone mineral density of the proximal femur from clinical CT images about?

Commercial software is generally needed to measure the areal bone mineral density (aBMD) of the proximal femur from clinical computed tomography (CT) images. This study developed and verified an open-source reproducible system to quantify CT-aBMD to screen osteoporosis using clinical CT images. Purpose For existing CT images acquired for various reasons other than osteoporosis, it might be beneficial to estimate areal BMD as assessed by dual-energy X-ray absorptiometry (DXA-based BMD) to ascertain the bone status based on DXA. In this study, we aimed to ( 1) develop an open-source reproducible measurement system to quantify DXA-based BMD from CT images and (2) validate its accuracy. Methods This study analyzed 75 pairs of hip CT and DXA images of women that were acquired for the preoperative assessment of total hip arthroplasty. From the CT images, the femur and a calibration phantom were automatically segmented using pre-trained codes/models available at https:// github. com/ keisu ke-uemura. The proximal femoral region was isolated by manually selected landmarks and was projected onto the coronal plane to measure the areal density (CT-aHU). The calibration phantom was employed to

Who reads Development of an open-source measurement system to assess the areal bone mineral density of the proximal femur from clinical CT images?

Author

Keisuke Uemura; Yoshito Otake; Masaki Takao; Hiroki Makino; Mazen Soufi; Makoto Iwasa; Nobuhiko Sugano; Yoshinobu Sato

Publisher

Springer Science and Business Media LLC

Published

2022

Language

EN

Field

Medicine (Health Sciences)