Can I read Aspirin Resistance in Cardiovascular Disease on EtoBox?

Aspirin Resistance in Cardiovascular Disease by Bryam Smith Molina is a document available to read on EtoBox.

What is Aspirin Resistance in Cardiovascular Disease about?

This document reviews mechanisms of aspirin resistance in cardiovascular disease. It discusses how aspirin works by inhibiting platelet cyclooxygenase 1 (COX-1) to suppress thromboxane A2 biosynthesis. However, in some patients aspirin is unable to prevent thrombosis due to incomplete COX-1 inhibition from factors like COX-2 expression in new platelets, drug interactions, or COX-1 variants. The document also notes enhanced biosynthesis of other eicosanoids like prostaglandins, leukotrienes, and isoprostanes

Author

Bryam Smith Molina

Language

EN