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Relation between mechanical properties and microstructure of human fetal membranes: An attempt towards a quantitative analysis by Mahmood Jabareen; Ajit Sankar Mallik; Grozdana Bilic; Andreas Hugo Zisch; Edoardo Mazza is a Medicine article available to read on EtoBox.
What is Relation between mechanical properties and microstructure of human fetal membranes: An attempt towards a quantitative analysis about?
## Objective: We sought to measure the mechanical baseline behavior of fetal membranes in order to determine constitutive mechanical model parameters for fetal membranes, and to examine their relation to molecular correlates for mechanical function, i.e. collagen and elastin. ## Study design: The uniaxial stress-strain response of nine human term fetal membranes was measured. methods of nonlinear continuum mechanics were applied for the analysis of the stress-strain curves. thickness of amnion and chorion were determined from histologic sections for each fetal membrane sample. complementary biochemical analysis was performed to quantify the soluble collagen and soluble elastin components for each sample. ## Results: We report a straightforward histologic modality for measurements of amnion and chorion thickness. average thickness of the amnion and chorion layers were 111+/-78 microm, and 431+/-113 microm, respectively, which are about twice larger than previously reported. the average content of acid-soluble elastin was 2.1% of wet weight and the one of pepsin/acetic acid-soluble collagen was 10.5% of dry weight. our data show an inverse proportionality between soluble elastin and
Who reads Relation between mechanical properties and microstructure of human fetal membranes: An attempt towards a quantitative analysis?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Mahmood Jabareen; Ajit Sankar Mallik; Grozdana Bilic; Andreas Hugo Zisch; Edoardo Mazza
- Publisher
- Elsevier BV
- Published
- 2009
- Language
- EN
- Field
- Medicine (Health Sciences)