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OR29-05 Sarcopenia, Low Bone Mineral Density And Hidden Obesity In Young Adult Men Living With HIV (MLWH): Prevalence And Relationship With Sex Steroids by De Vincentis, Sara (author);Chiara Decaroli, Maria (author);Greco, Carla (author);Diazzi, Chiara (author);Fanelli, Flaminia (author);Mezzullo, Marco (author);Pagotto, Uberto (author);Guaraldi, Giovanni (author);Rochira, Vincenzo (author) is a Medicine article available to read on EtoBox.

What is OR29-05 Sarcopenia, Low Bone Mineral Density And Hidden Obesity In Young Adult Men Living With HIV (MLWH): Prevalence And Relationship With Sex Steroids about?

## Abstract **Disclosure: S. De Vincentis:** None. **M. Decaroli:** None. **C. Greco:** None. **C. Diazzi:** None. **F. Fanelli:** None. **M. Mezzullo:** None. **U. Pagotto:** None. **G. Guaraldi:** None. **V. Rochira:** None. **Background:** HIV is associated with decreased bone mineral density (BMD) and decreased muscle mass. Osteoporosis and sarcopenia often co-exist and their onset is multifactorial. Sex steroids play a key role in the homeostasis of bone health and body composition in HIV-uninfected men, but data about their role in MLWH are scanty. AIM: To investigate the frequency of low BMD and sarcopenia and their relationship with gonadal function in MLWH younger than 50. **Methodology:** Prospective, cross-sectional, observational study on MLWH with ongoing antiretroviral therapy. Body composition and BMD were obtained by dual-energy X-ray absorptiometry (DXA). Sarcopenia was defined as appendicular lean mass/height^2^ (ALMI) <7.26 kg/m^2^; low BMD was defined for Z-score 20%. Serum total testosterone (TT) and estradiol (E2) were measured by liquid chromatography-tandem mass spectrometry; free testosterone (cFT) was calculated by Vermeulen equation. **Results:** A total

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Author

De Vincentis, Sara (author);Chiara Decaroli, Maria (author);Greco, Carla (author);Diazzi, Chiara (author);Fanelli, Flaminia (author);Mezzullo, Marco (author);Pagotto, Uberto (author);Guaraldi, Giovanni (author);Rochira, Vincenzo (author)

Publisher

The Endocrine Society

Published

2023

Field

Medicine (Health Sciences)