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Can I read Target Selection for Alignment of Chromatographic Signals Obtained Using Monochannel Detectors on EtoBox?
Target Selection for Alignment of Chromatographic Signals Obtained Using Monochannel Detectors by M. Daszykowski; B. Walczak is a Chemistry article available to read on EtoBox.
What is Target Selection for Alignment of Chromatographic Signals Obtained Using Monochannel Detectors about?
The alignment of instrumental signals, such as chromatograms, is regarded as an important step before applying multivariate chemometric techniques for data analysis. Nowadays, many alignment techniques are available and they differ in achieving their goal. They can correct peak shifts in a set of chromatograms with differing degrees of success. Almost all alignment techniques, with few exceptions [e.g., W. Yu, B. Wu, N. Lin, K. Stone, K. Williams, H. Zhao, Comput. Biol. Chem. 30 (2006) 27], require a careful choice of the target profile. The selection of a target signal is not an easy task and some difficulties related to this selection are discussed in this paper. An analysis of several simulated sets of chromatographic signals showed that the target selection can be a crucial step if the aligned signals are then used as input to unsupervised approaches, such as, e.g., principal component analysis and to supervised methods like discriminant partial least squares. Different proposals for target selection known-to-date are reviewed. As demonstrated in our study the target profile with the highest correlation coefficient among all the signals studied gave the most satisfactory result
Who reads Target Selection for Alignment of Chromatographic Signals Obtained Using Monochannel Detectors?
It is typically read by researchers, students, and practitioners in Chemistry.
- Author
- M. Daszykowski; B. Walczak
- Publisher
- Elsevier Science; Elsevier ; Elsevier BV (ISSN 1873-3778)
- Published
- 2007
- Language
- EN
- Field
- Chemistry (Physical Sciences)