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Can I read Gut microbiome studies in CKD: opportunities, pitfalls and therapeutic potential on EtoBox?
Gut microbiome studies in CKD: opportunities, pitfalls and therapeutic potential by Hubert Krukowski; Sophie Valkenburg; Avra-Melina Madella; Johan Garssen; Jeroen van Bergenhenegouwen; Saskia Adriana Overbeek; Geert R. B. Huys; Jeroen Raes; Griet Glorieux is a Medicine article available to read on EtoBox.
What is Gut microbiome studies in CKD: opportunities, pitfalls and therapeutic potential about?
Interest in gut microbiome dysbiosis and its potential association with the development and progression of chronic kidney disease (CKD) has increased substantially in the past 6 years. In parallel, the microbiome field has matured considerably as the importance of host-related and environmental factors is increasingly recognized. Past research output in the context of CKD insufficiently considered the myriad confounding factors that are characteristic of the disease. Gut microbiota-derived metabolites remain an interesting therapeutic target to decrease uraemic (cardio)toxicity. However, future studies on the effect of dietary and biotic interventions will require harmonization of relevant readouts to enable an in-depth understanding of the underlying beneficial mechanisms. High-quality standards throughout the entire microbiome analysis workflow are also of utmost importance to obtain reliable and reproducible results. Importantly, investigating the relative composition and abundance of gut bacteria, and their potential association with plasma uraemic toxins levels is not sufficient. As in other fields, the time has come to move towards in-depth quantitative and functional explora
Who reads Gut microbiome studies in CKD: opportunities, pitfalls and therapeutic potential?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Hubert Krukowski; Sophie Valkenburg; Avra-Melina Madella; Johan Garssen; Jeroen van Bergenhenegouwen; Saskia Adriana Overbeek; Geert R. B. Huys; Jeroen Raes; Griet Glorieux
- Publisher
- Springer Science and Business Media LLC
- Published
- 2022
- Language
- EN
- Field
- Medicine (Health Sciences)