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Should a Benzodiazepine Antagonist Be Used in Unconscious Patients Presenting to the Emergency Department? by Adeline Su-Yin Ngo; Charles Rabind Anthony; Miny Samuel; Evelyn Wong; R. Ponampalam is a Medicine article available to read on EtoBox.

What is Should a Benzodiazepine Antagonist Be Used in Unconscious Patients Presenting to the Emergency Department? about?

Patients in coma with suspected drug poisoning are commonly encountered in the emergency department. Benzodiazepines are one of the most commonly used drugs in self-poisoning. Flumazenil, a benzodiazepine antagonist has been suggested as a diagnostic and treatment tool in suspected poisoning of unclear cause, but caution is required due to potential side effects. No systemic review of this literature has been done on this topic. ## Objectives: The aim of this study is to examine if flumazenil should be used in patients with coma from suspected drug poisoning. ## Search strategy: Randomised controlled trials were identified from the cochrane library, pubmed and embase. bibliographies from included studies, known reviews and texts were searched. content experts were contacted. ## Selection criteria: Randomised controlled trials were eligible for inclusion. studies were included if patients who presented with altered mental state from suspected drug poisoning were treated with intravenous flumazenil as compared to placebo. ## Data collection and analysis: Data were extracted and methodological quality was assessed independently by two reviewers. ## Main results: Seven randomised contr

Who reads Should a Benzodiazepine Antagonist Be Used in Unconscious Patients Presenting to the Emergency Department??

Author

Adeline Su-Yin Ngo; Charles Rabind Anthony; Miny Samuel; Evelyn Wong; R. Ponampalam

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0300-9572)

Published

2007

Language

EN

Field

Medicine (Health Sciences)