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Can I read Protein Crystallography in Drug Discovery, Volume 20 (Methods and Principles in Medicinal Chemistry) on EtoBox?
Protein Crystallography in Drug Discovery, Volume 20 (Methods and Principles in Medicinal Chemistry) by Robert E. Babine, Sherin S. Abdel-Meguid, Raimund Mannhold, Hugo Kubinyi, Gerd Folkers is a nonfiction available to read on EtoBox.
What is Protein Crystallography in Drug Discovery, Volume 20 (Methods and Principles in Medicinal Chemistry) about?
The rational, structure-based approach has become standard in present-day drug design. As a consequence, the availability of high-resolution structures of target proteins is more often than not the basis for an entire drug development program. Protein structures suited for rational drug design are almost exclusively derived from crystallographic studies, and drug developers are relying heavily on the power of this method.Here, researchers from leading pharmaceutical companies present valuable first-hand information, much of it published for the first time. They discuss strategies to derive high-resolution structures for such important target protein classes as kinases or proteases, as well as selected examples of successful protein crystallographic studies. A special section on recent methodological developments, such as for high-throughput crystallography and microcrystallization, is also included.A valuable companion for crystallographers involved in protein structure determination as well as drug developers pursuing the structure-based approach for use in their daily work.
Who reads Protein Crystallography in Drug Discovery, Volume 20 (Methods and Principles in Medicinal Chemistry)?
It is typically read by self-directed learners exploring a subject in depth.
Common subject areas: history, science, philosophy, social sciences.
- Author
- Robert E. Babine, Sherin S. Abdel-Meguid, Raimund Mannhold, Hugo Kubinyi, Gerd Folkers
- Publisher
- Wiley-VCH GmbH
- Published
- 2004
- Language
- EN
- ISBN
- 9783527601875
- Category
- nonfiction
- Subjects
- Medical, Science, Chemistry
Other editions & translations
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