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Can I read Rate of Lobar Collapse and/or Urgent Thoracic RT following Initial Chemotherapy for Advanced Non-small Cell Carcinoma (NSCLC): Implications for Selecting Patients for Early Intervention with Thoracic RT on EtoBox?
Rate of Lobar Collapse and/or Urgent Thoracic RT following Initial Chemotherapy for Advanced Non-small Cell Carcinoma (NSCLC): Implications for Selecting Patients for Early Intervention with Thoracic RT by D.S. Higginson; R.C. Chen; M.A. Socinski; D.E. Morris; J.G. Rosenman; J.S. Halle; L.B. Marks is a Medicine article available to read on EtoBox.
What is Rate of Lobar Collapse and/or Urgent Thoracic RT following Initial Chemotherapy for Advanced Non-small Cell Carcinoma (NSCLC): Implications for Selecting Patients for Early Intervention with Thoracic RT about?
Materials/Methods: The records of all patients completing two courses of SBRT at the University of Rochester from December 2000 to February 2010 were reviewed. Patients who underwent retreatment with SBRT for a LF in the lung (within 1 cm of the original gross tumor volume) were included in this study. Treatments were performed with the Novalis linear accelerator, using the ExacTrac system for localization. All doses were prescribed to isocenter. A planning treatment volume, with a 7 mm axial and 10-11 mm craniocaudal expansion, received 80% or greater of the prescription dose. Results: A total of 25 tumors in 23 patients were treated with two courses of SBRT. Median age was 69 yrs. The retreated tumors were from medically inoperable stage I lung cancer (n = 8), stage II-IV lung cancer (n = 9), or oligometastatic disease from a nonlung primary (n = 8). Six lesions were central, 19 were peripheral. Median lesion size before the first treatment was 2.4 cm (mean 2.8). Median (mean, range) prescribed dose for the first course of SBRT was 50 Gy (50.8 Gy, 35-60 Gy) in 10 (10.2, 5-13) fractions. Initial partial or complete response, before subsequent recurrence, was seen in 13 tumors (52%
Who reads Rate of Lobar Collapse and/or Urgent Thoracic RT following Initial Chemotherapy for Advanced Non-small Cell Carcinoma (NSCLC): Implications for Selecting Patients for Early Intervention with Thoracic RT?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- D.S. Higginson; R.C. Chen; M.A. Socinski; D.E. Morris; J.G. Rosenman; J.S. Halle; L.B. Marks
- Publisher
- Elsevier Science; Elsevier ; Elsevier BV (ISSN 0360-3016)
- Published
- 2010
- Language
- EN
- Field
- Medicine (Health Sciences)