Can I read 2025 Article 2280 on EtoBox?
2025 Article 2280 by Adriano Roque is a document available to read on EtoBox.
What is 2025 Article 2280 about?
The study explores the use of SK56, an AI-screened peptide, as a blocker of gasdermin D (GSDMD-NT) pores to mitigate pyroptosis and associated inflammatory responses. SK56 effectively inhibits cytokine release and prevents cell death in various models, showing promise as a therapeutic strategy for conditions exacerbated by excessive inflammation. The findings suggest that targeting GSDMD-NT may offer new treatment avenues for diseases linked to dysregulated inflammasome activity.
- Author
- Adriano Roque
- Language
- EN