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Mutagenicity of Urine from Young Male Smokers and Nonsmokers by Hiromi Kawano; Takeo Inamasu; Minoru Ishizawa; Noburu Ishinishi; Joichi Kumazawa is a Medicine article available to read on EtoBox.

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The mutagenicity of urine from a healthy population of young adult men (average age of 23 years), including 61 smokers and 107 nonsmokers, was investigated with the Salmonella/microsome test using the tester strain S typhymurium TA 98 In quantifying the assay, the use of dichloromethane was suitable for eluting the mutagenicity of smokers' urine from the XAD-2 resin column We assayed mutagenicity in condensates of such dichloromethane eluates and found that the mutagenicity of smokers' urine was significantly higher than that of nonsmokers' urine In the smokers' group, correlation coefficient between "the mutagenicity of the urine" and "the actual number of cigarettes smoked on the day of urine collection" or "the average number of cigarettes smoked per day" was statistically significant at 0 266 or 0 454, respectively Our results suggest a correlation between the increase of mutagens in urine and smoking habits.

Who reads Mutagenicity of Urine from Young Male Smokers and Nonsmokers?

Author

Hiromi Kawano; Takeo Inamasu; Minoru Ishizawa; Noburu Ishinishi; Joichi Kumazawa

Publisher

Springer-Verlag; Springer Verlag; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 0340-0131)

Published

1987

Language

EN

Field

Medicine (Health Sciences)