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Prognostic Value of the Combination of Neutrophil-to-lymphocyte Ratio, Monocyte-to-lymphocyte Ratio and Platelet-to-lymphocyte Ratio on Mortality in Patients on Maintenance Hemodialysis by Jiaxian Liao; Dongyan Wei; Chenghui Sun; Yuqi Yang; Yinxia Wei; Xinhui Liu is a Medicine article available to read on EtoBox.

What is Prognostic Value of the Combination of Neutrophil-to-lymphocyte Ratio, Monocyte-to-lymphocyte Ratio and Platelet-to-lymphocyte Ratio on Mortality in Patients on Maintenance Hemodialysis about?

## Abstract ## Background Hemodialysis (HD) is the most important renal replacement therapy for patients with end-stage kidney disease (ESKD). Systemic inflammation is a risk factor of mortality in HD patients. Neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), and platelet-to-lymphocyte ratio (PLR) are new inflammatory markers. However, previous studies have inconsistent conclusions about the predictive value of NLR, MLR and PLR on mortality of HD patients. The aim of this study was to establish an inflammation scoring system by including NLR, MLR and PLR, and evaluate the association between the inflammation score and all-cause and cardiovascular mortality in HD patients. ## Methods In this single center retrospective cohort study, 213 incident HD patients from January 1, 2015 to December 31, 2020 were included. Baseline demographic and clinical data and laboratory measurements were collected. According to the optimal cut-off values, NLR, MLR and PLR were assigned 0 or 1 point, respectively. Then, the inflammation score was obtained by adding the NLR, MLR and PLR scores. All patients were followed until July 31, 2021. The associations of the inflammation sc

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Author

Jiaxian Liao; Dongyan Wei; Chenghui Sun; Yuqi Yang; Yinxia Wei; Xinhui Liu

Publisher

Springer Science and Business Media LLC

Published

2022

Language

EN

Field

Medicine (Health Sciences)