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Antibacterial potential of Antarctic lichens against human pathogenic Gram-positive bacteria by Babita Paudel; Hari Datta Bhattarai; Jin Sung Lee; Soon Gyu Hong; Hyun Woung Shin; Joung Han Yim is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

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## Abstract Extracts from five Antarctic lichens (L3, __Stereocaulon alpinum__; L5, __Ramalina terebrata__; L6, __Caloplaca__ sp.; L8, __Lecanora__ sp.; and L17, __Caloplaca regalis__) were tested for antimicrobial activities against several clinically important microbes by disk diffusion. The minimum inhibitory concentration (MIC) of each extract was determined by a broth dilution method. Extracts from L3, L5, L6 and L8 were active against two Gram(+) strains. __B. subtilis__ was more sensitive to lichen extracts (except L5) than __S. aureus__. The MIC of lichen extracts against __B. subtilis__ and __S. aureus__ was observed from 36.7 ± 0.3 to 953.8 ± 85.8 μg/mL and 68.5 ± 0.6 to >1000 μg/mL, respectively. Comparisons of MIC values of Antarctic lichen crude extracts to previously published MIC values of some reported lichen metabolites against Gram(+) bacteria indicated that Antarctic lichens might be an enriched source of effective antibacterial agents against clinically relevant Gram(+) species. Copyright © 2008 John Wiley & Sons, Ltd.

Who reads Antibacterial potential of Antarctic lichens against human pathogenic Gram-positive bacteria?

Author

Babita Paudel; Hari Datta Bhattarai; Jin Sung Lee; Soon Gyu Hong; Hyun Woung Shin; Joung Han Yim

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0951-418X)

Published

2008

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)