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Can I read Adverse Cutaneous Effects of Mitogen‐activated Protein Kinase Inhibitors in Children on EtoBox?
Adverse Cutaneous Effects of Mitogen‐activated Protein Kinase Inhibitors in Children by Victoria Lucia Dávila Osorio; María Asunción Vicente; Eulalia Baselga; Hector Salvador; Ofelia Cruz; Carolina Prat is a Medicine article available to read on EtoBox.
What is Adverse Cutaneous Effects of Mitogen‐activated Protein Kinase Inhibitors in Children about?
## Background: Mitogen-activated protein kinase inhibitors (meki) are currently used for the treatment of central nervous system tumors in children and have shown promising results. cutaneous adverse effects are among the most common toxicities described in adults, but few studies exist in pediatric patients. ## Objective: We aimed to describe the cutaneous adverse effects associated with meki in pediatric patients. ## Methods: A retrospective study was carried out at our pediatric hospital in barcelona, spain, in patients undergoing treatment with meki. ## Results: Sixty-one children between 1 and 18 years of age were included. all patients developed cutaneous toxicity. eczema, hair abnormalities, oral aphthae, and paronychia were among the most common cutaneous side effects. ## Conclusions: Recognizing skin toxicity in pediatric patients under treatment with meki is essential to establishing appropriate education and therapy, thereby improving treatment tolerability and minimizing avoidable interruptions in treatment.
Who reads Adverse Cutaneous Effects of Mitogen‐activated Protein Kinase Inhibitors in Children?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Victoria Lucia Dávila Osorio; María Asunción Vicente; Eulalia Baselga; Hector Salvador; Ofelia Cruz; Carolina Prat
- Publisher
- Wiley
- Published
- 2020
- Language
- EN
- Field
- Medicine (Health Sciences)