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This document describes the identification of a new high-incidence antigen named GUTI in the Cromer blood group system, associated with a point mutation in the decay-accelerating factor (DAF). The study involved sequence analysis and PCR-RFLP assays, revealing a substitution mutation at position 719G>A in DAF, which affects the expression of the GUTI antigen. The findings indicate that GUTI is characterized by an amino acid change at position 206 in SCR4 of DAF and has a notable allele incidence among Chile

Author

Macarena

Language

EN