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Can I read Measurement of intervertebral disc pressure with T ~1ρ~ MRI on EtoBox?
Measurement of intervertebral disc pressure with T ~1ρ~ MRI by Chenyang Wang; Walter Witschey; Mark A. Elliott; Arijitt Borthakur; Ravinder Reddy is a Medicine article available to read on EtoBox.
What is Measurement of intervertebral disc pressure with T ~1ρ~ MRI about?
The aim of this study is to demonstrate T(1ρ) MRI's capability for measuring intervertebral disc osmotic pressure. Self-coregistered sodium and T(1ρ) -weighted MR images were acquired on ex vivo bovine intervertebral discs (N = 12) on a 3 T clinical MRI scanner. The sodium MR images were used to calculate effective nucleus pulposus fixed-charge-density (mean = 138.2 ± 27.6 mM) and subsequently osmotic pressure (mean = 0.53 ± 0.18 atm), whereas the T(1ρ) -weighted images were used to compute T(1ρ) relaxation maps. A significant linear correlation (R = 0.56, P < 0.01) between nucleus pulposus fixed-charge-density and T(1ρ) relaxation time constant was observed. More importantly, a significant power correlation (R = 0.72, P < 0.01) between nucleus pulposus osmotic pressure as predicted by sodium MRI and T(1ρ) relaxation time constant was also observed. The current clinical method for assessing disc pressure is discography, which is an invasive procedure that has been shown to have negative effects on disc biomechanical and biochemical properties. In contrast, T(1ρ) MRI is noninvasive and can be easily implemented in a clinical setting due to its superior signal-to-noise ratio compared
Who reads Measurement of intervertebral disc pressure with T ~1ρ~ MRI?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Chenyang Wang; Walter Witschey; Mark A. Elliott; Arijitt Borthakur; Ravinder Reddy
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0740-3194)
- Published
- 2010
- Language
- EN
- Field
- Medicine (Health Sciences)