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Free Radical Biology & Medicine: Long Chen, Lei Liu, Shile Huang by Mariano Perez is a document available to read on EtoBox.
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The document discusses how cadmium activates the MAPK pathway through inducing reactive oxygen species and inhibiting protein phosphatases 2A and 5. It finds that cadmium induces ROS, leading to apoptosis in neuronal cells, which is prevented by antioxidants. It also finds that cadmium-induced ROS inhibits PP2A and PP5, activating ERK1/2 and JNK pathways and resulting in caspase-dependent and independent apoptosis.
- Author
- Mariano Perez
- Language
- EN