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Mild Gestational Hyperglycaemia as a Risk Factor for Metabolic Syndrome in Pregnancy and Adverse Perinatal Outcomes by Carlos Antonio Negrato; Lois Jovanovic; Marcos Antonio Tambascia; Iracema de Mattos Paranhos Calderon; Bruno Geloneze; Adriano Dias; Marilza Vieira Cunha Rudge is a Medicine article available to read on EtoBox.
What is Mild Gestational Hyperglycaemia as a Risk Factor for Metabolic Syndrome in Pregnancy and Adverse Perinatal Outcomes about?
## Abstract ## Objective The aims of this study were to evaluate the prevalence of metabolic syndrome (MS) in a cohort of pregnant women with a wide range of glucose tolerance, pre‐pregnancy risk factors for MS during pregnancy and the effects of MS in the occurrence of adverse perinatal outcomes. ## Research Design and Methods One hundred and thirty six women with positive screening for gestational diabetes (GDM) were classified by two diagnostic methods: glycaemic profile and 100 g oral glucose tolerance test (OGTT) as normoglycaemic, mild gestational hyperglycaemic, GDM, and overt GDM. Markers of insulin resistance were measured between 24–28 and 36th week of gestation, and 6 weeks after delivery. ## Results The prevalence of MS was 0; 20.0; 23.5 and 36.4% in normoglycaemic, mild hyperglycaemic, GDM and overt GDM groups, respectively. Previous history of GDM with or without insulin use, body mass index (BMI) ≥ 25, hypertension, family history of diabetes in first‐degree relatives, non‐Caucasian ethnicity, history of prematurity and polyhydramnios were statistically significant pre‐pregnancy predictors for MS in the index pregnancy, that by its turn increased the occurrence of ad
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- Author
- Carlos Antonio Negrato; Lois Jovanovic; Marcos Antonio Tambascia; Iracema de Mattos Paranhos Calderon; Bruno Geloneze; Adriano Dias; Marilza Vieira Cunha Rudge
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1520-7552)
- Published
- 2008
- Language
- EN
- Field
- Medicine (Health Sciences)