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Can I read MRI features of low-grade and high-grade chondrosarcoma in enchondromatosis on EtoBox?

MRI features of low-grade and high-grade chondrosarcoma in enchondromatosis by Ban Sharif; Ramanan Rajakulasingam; Shahab Sharifi; Paul O’Donnell; Asif Saifuddin is a Medicine article available to read on EtoBox.

What is MRI features of low-grade and high-grade chondrosarcoma in enchondromatosis about?

Objective To identify magnetic resonance imaging (MRI) features which aid differentiation of low-grade chondral tumours (LGCT-enchondroma and grade 1 chondrosarcoma) from high-grade chondral tumours (HGCT) in patients with enchondromatosis. Materials and method Approval from our local Research and Innovation Centre of The Institute of Orthopaedics was gained. Patients with enchondromatosis who had biopsy and/or resection of chondral lesions over a 13-year period were identified. The pre-biopsy MRI study was assessed by two experienced musculoskeletal radiologists for tumour origin (intramedullary or surface), cortical expansion, cortical destruction, bone marrow oedema, periosteal reaction, soft tissue mass and soft tissue oedema. MRI features were compared with the final histopathological diagnosis. ## Results The study group comprised 25 males and 16 females, with a mean age of 34.9 years (range 6-81 years). Fifty-nine lesions were assessed (12 patients had > 1 tumour treated), including 43 LGCT and 16 HGCT. Significant MRI features suggesting malignant transformation to HGCT for both observers included bone oedema (p = < 0.001 and 0.002), periosteal reaction (p = 0.01) and soft

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Author
Ban Sharif; Ramanan Rajakulasingam; Shahab Sharifi; Paul O’Donnell; Asif Saifuddin
Publisher
Springer Science and Business Media LLC
Published
2021
Language
EN
Field
Medicine (Health Sciences)

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