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This research article investigates how biomolecular condensates can induce local membrane potentials in cells, particularly through interactions with lipid membranes. Using a model system of Giant Unilamellar Vesicles (GUVs) and electrochromic dyes, the study demonstrates that the wetting of membranes by poly-lysine/ATP condensates can alter membrane potential, with implications for biological processes like neuronal signaling. The findings suggest that the charge of condensates plays a significant role in

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nathanunpassodalcielo
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