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The Influence of Different Plasticizers and Polymers on the Mechanical and Thermal Properties, Porosity and Drug Permeability of Free Shellac Films by Basel Qussi; Wolfgang G. Suess is a Pharmacology, Toxicology and Pharmaceutics article available to read on EtoBox.
What is The Influence of Different Plasticizers and Polymers on the Mechanical and Thermal Properties, Porosity and Drug Permeability of Free Shellac Films about?
The effect of triethyl citrate (TEC) and different molecular weights and concentrations of polyethylene glycol (PEG), in addition to the effect of different water-soluble polymers and dispersions at different levels, hydroxypropyl methylcellulose (HPMC), methylcellulose (MC), carbomer 940, polyvinyl alcohol (PVA), ethyl cellulose (EC), on the mechanical and thermal properties, drug permeability, and porosity of free shellac films were investigated. Shellac films were cast from aqueous solutions, and their mechanical properties were studied by tensile test. Thermal analyses were performed using differential scanning calorimetry (DSC). The results showed that the addition of plasticizer caused a decrease in both elastic modulus and glass transition temperature (T(g)) and an increase in elongation at break of free shellac films. This effect was related to the concentrations of plasticizers. Different molecular weights of PEGs have different plasticization mechanisms.Moreover, the incorporation of different amounts of HPMC, MC, or carbomer in free shellac films caused an increase in the flexibility, decrease in T(g), and a marked increase in drug permeability of free shellac films, whe
Who reads The Influence of Different Plasticizers and Polymers on the Mechanical and Thermal Properties, Porosity and Drug Permeability of Free Shellac Films?
It is typically read by researchers, students, and practitioners in Pharmacology, Toxicology and Pharmaceutics.
- Author
- Basel Qussi; Wolfgang G. Suess
- Publisher
- Informa UK Limited
- Published
- 2006
- Language
- EN
- Field
- Pharmacology, Toxicology and Pharmaceutics (Life Sciences)