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CTL Mediated Pathways by Sazid Hasan Limon is a document available to read on EtoBox.

What is CTL Mediated Pathways about?

The document outlines two CTL-mediated pathways for killing target cells: the Fas-FasL pathway and the perforin-granzyme pathway. The Fas-FasL pathway involves ligand-receptor binding leading to caspase activation and apoptosis, while the perforin-granzyme pathway utilizes perforin to create pores for granzyme entry, triggering mitochondrial involvement and an intrinsic apoptotic pathway. Key differences between the two pathways include their initiation mechanisms, effector molecules, and the role of mitoch

Author

Sazid Hasan Limon

Language

EN