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Can I read Echinochrome Pigment Extracted from Sea Urchin Suppress the Bacterial Activity, Inflammation, Nociception, and Oxidative Stress Resulted in the Inhibition of Renal Injury in Septic Rats on EtoBox?
Echinochrome Pigment Extracted from Sea Urchin Suppress the Bacterial Activity, Inflammation, Nociception, and Oxidative Stress Resulted in the Inhibition of Renal Injury in Septic Rats by Shimaa A. Sadek; Sarah S. Hassanein; Ayman S. Mohamed; Amel M. Soliman; Sohair R. Fahmy is a Agricultural and Biological Sciences article available to read on EtoBox.
What is Echinochrome Pigment Extracted from Sea Urchin Suppress the Bacterial Activity, Inflammation, Nociception, and Oxidative Stress Resulted in the Inhibition of Renal Injury in Septic Rats about?
The current study aimed to evaluate the antibacterial, anti-inflammatory, analgesic, and renoprotective effects of echinochrome pigment extracted from sea urchin. The disk diffusion method was used for the antibacterial activity of echinochrome against four different bacterial strains; Salmonella typhimurium, Pseudomonas aeroginosa, Staphylococcus aureus, and Listeria monocytogenes. While, acetic acid-induced writhing, formalin-induced licking, and hot plate latency assays evaluate the analgesic activity. The biochemical and oxidative stress markers of kidneys, as well as the histopathological examination, were measured to evaluate the renoprotective activity of echinochrome for cecal ligation and puncture-induced renal injury in rats. Echinochrome pigment exhibited in vitro antibacterial activity against all aforementioned bacterial species besides a powerful anti-inflammatory impact in vitro by the effective stabilization of the RBCs membrane and in vivo by decrease levels of serum IL6 and TNFα. What's more, echinochrome showed a notable analgesic efficacy as well as an enhancement of the kidney's biochemical markers, oxidative stress status, and histopathological screening. Ech
Who reads Echinochrome Pigment Extracted from Sea Urchin Suppress the Bacterial Activity, Inflammation, Nociception, and Oxidative Stress Resulted in the Inhibition of Renal Injury in Septic Rats?
It is typically read by researchers, students, and practitioners in Agricultural and Biological Sciences.
- Author
- Shimaa A. Sadek; Sarah S. Hassanein; Ayman S. Mohamed; Amel M. Soliman; Sohair R. Fahmy
- Publisher
- Hindawi Limited
- Published
- 2021
- Language
- EN
- Field
- Agricultural and Biological Sciences (Life Sciences)