Can I read C‐reactive Protein in the Diagnosis of Deep Vein Thrombosis on EtoBox?

C‐reactive Protein in the Diagnosis of Deep Vein Thrombosis by Robert A. Bucek; Markus Reiter; Peter Quehenberger; Erich Minar is a Medicine article available to read on EtoBox.

What is C‐reactive Protein in the Diagnosis of Deep Vein Thrombosis about?

**Summary.** The role of C‐reactive protein (CRP) in the diagnosis of suspected deep vein thrombosis (DVT) and a possible advantage of its additional evaluation with D‐dimer has not been clearly evaluated. We therefore studied plasma CRP and D‐dimer levels in 233 consecutive patients with suspected DVT; the final diagnosis was based on the results of colour duplex ultrasound or venography. DVT was diagnosed in 31·3%. CRP and D‐dimer correlated significantly (__r =__ 0·64, __P__ < 0·01); both were increased significantly in patients suffering from DVT (__P__ < 0·001). Multivariate analysis revealed a significant influence of the presence of DVT (__P__ < 0·001), the presence of malignancy (__P__ < 0·001) and the presence of inflammatory diseases (__P =__ 0·009) on plasma CRP, while there was no significant influence of the duration of symptoms (__P =__ 0·30). The sensitivity (75%__vs__ 93%) to specificity (69%__vs__ 55%) relationship showed inferior results for CRP compared with D‐dimer; its additional evaluation did not improve the diagnostic value of D‐dimer. We conclude that CRP can provide additional information neither for the diagnostic process in patients with suspected DVT no

Who reads C‐reactive Protein in the Diagnosis of Deep Vein Thrombosis?

Author

Robert A. Bucek; Markus Reiter; Peter Quehenberger; Erich Minar

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0007-1048)

Published

2002

Language

EN

Field

Medicine (Health Sciences)