Can I read Bone and Fat on EtoBox?

Bone and Fat by Francisco J.A. de Paula; Ingrid Dick-de-Paula; Masanobu Kawai; Clifford J. Rosen is a book available to read on EtoBox.

What is Bone and Fat about?

Bone and adipose tissue were classically identified as sites involved with the storage of mineral and fat, respectively. Compelling evidence shows that adipose tissue and bone remodeling are orchestrated by a complex and dynamic network including central nervous system, endocrine, and paracrine/autocrine components. Adipocytes and bone cells are integrated in the control of satiety, energy storage, and insulin secretion and sensitivity, as well as in the maintenance of bone strength. The rising prevalence of osteoporosis and obesity-related disorders on the one hand and the recognition of common mechanisms linking bone to metabolic changes on the other hand indicate that obesity/metabolic syndrome and osteoporosis may be related disorders. The complexity of this interrelationship is unique due to the heterogeneous behavior of adipose tissue, namely, subcutaneous versus visceral, white versus brown, and the diversity of cells involved in bone remodeling (osteoblast, osteoclast, and osteocyte). This chapter intends to update the reader about the physiological integration between adipocyte and bone cells and the role of hormonal factors that regulate bone and energy metabolism.

Author

Francisco J.A. de Paula; Ingrid Dick-de-Paula; Masanobu Kawai; Clifford J. Rosen

Publisher

Elsevier Science & Technology; Academic Press

Published

2021

Language

EN

ISBN

9780128130735

Subjects

Science, Medical, Stem