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Cutaneous Manifestations, Clinical Characteristics, and Prognosis of Patients With Systemic Sclerosis Sine Scleroderma: Data From the International EUSTAR Database by Alain Lescoat; Suiyuan Huang; Patricia E. Carreira; Elise Siegert; Jeska de Vries-Bouwstra; Jörg H. W. Distler; Vanessa Smith; Francesco Del Galdo; Branimir Anic; Nemanja Damjanov; Simona Rednic; Camillo Ribi; Dominique Farge Bancel; Anna-Maria Hoffmann-Vold; Armando Gabrielli; Oliver Distler; Dinesh Khanna; Yannick Allanore; Marco Matucci Cerinic; Ulrich Walker; Florenzo Iannone; Radim Becvar; Otylia Kowal Bielecka; Carmen Pizzorni; Francesco Ciccia; Elise Siegert; Simona Rednic; Panayiotis G. Vlachoyiannopoulos; Jiri Stork; Murat Inanc; Patricia E. Carreira; Srdan Novak; László Czirják; Michele Iudici; Eugene J. Kucharz; Katja Perdan-Pirkmajer; Bernard Coleiro; Gianluca Moroncini; Dominique Farge Bancel; Roger Hesselstrand; Mislav Radic; Alexandra Balbir-Gurman; Andrea Lo Monaco; Raffaele Pellerito; Alessandro Giollo; Jadranka Morovic-Vergles; Christopher Denton; Madelon Vonk; Nemanja Damjanov; Jörg Henes; Vera Ortiz Santamaria; Stefan Heitmann; Dorota Krasowska; Paul Hasler; Michaela Kohm; Ivan Foeldvari; Gianluigi Bajocchi; Maria João Salvador; Bojana Stamenkovic; Carlo F. Selmi; Mohammed Tikly; Lidia P. Ananieva; Ariane Herrick; Ulf Müller-Ladner; Klaus Søndergaard; Francesco Puppo; Merete Engelhart; Gabriela Szücs; Carlos de la Puente; Valeria Riccieri; Ruxandra Maria Ionescu; Ami Sha; Ana Maria Gheorghiu; Cord Sunderkötter; Jörg Distler; Francesca Ingegnoli; Luc Mouthon; Vanessa Smith; Francesco Paolo Cantatore; Susanne Ullman; Carlos Alberto von Mühlen; Maria Rosa Pozzi; Kilian Eyerich; Piotr Wiland; Marie Vanthuyne; Juan Jose Alegre-Sancho; Kristine Herrmann; Ellen De Langhe; Branimir Anic; Marko Baresic; Miroslav Mayer; Maria Üprus; Kati Otsa; Sule Yavuz; Brigitte Granel; Carolina de Souza Müller; Svetlana Agachi; Simon Stebbings; Alessandro Mathieu; Alessandra Vacca; Percival D. Sampaio-Barros; Lisa Stamp; Kamal Solanki; Douglas Veale; Esthela Loyo; Carmen Tineo; Sergio Toloza; Mengtao Li; Walid Ahmed Abdel Atty Mohamed; Jacek Olas; Fahrettin Oksel; Figen Yargucu; Cristina-Mihaela Tanaseanu; Rosario Foti; Codrina Ancuta; Daniel E. Furst; Britta Maurer; Jacob van Laar; Marzena Olesinska; Cristiane Kayser; Nihal Fathi; Paloma García de la Peña Lefebvre; Jorge Juan Gonzalez Martin; Patrick Carpentier; Bernard Imbert; Camille Francès; Patricia Senet; Jean Sibilia; Ira Litinsky; Jean Luc Senécal; Martial Koenig; France Joval; Grodzicky Tamara; Francesco Del Galdo; Goda Seskute; Lesley Ann Saketkoo; Eduardo Kerzberg; Washington Bianchi; Breno Valdetaro Bianchi; Ivan Castellví; Jasminka Milas-Ahic; Roberta Visevic; Massimiliano Limonta; Doron Rimar; Maura Couto; François Spertini; Antonella Marcoccia; Sarah Kahl; Vivien M. Hsu; Thierry Martin; Sergey Moiseev; Pavel Novikov; Lorinda S. Chung; Tim Schmeiser; Dominik Majewski; Zbigniew Zdrojewski; Julia Martínez-Barrio; Dinesh Khanna; Vera Bernardino; Lelita Santo; Yair Levy; Elena Rezus; Omer Nuri Pamuk; Daniel Brito de Araujo; Piercarlo Sarzi Puttini; Marek Brzosko; Hadi Poormoghim; Marta Maman; Ina Kötter; Giovanna Cuomo; Francis Gaches; Laura Belloli; Petros Sfikakis; Juliana Markus; Daniel Furst; Ana-Maria Ramazan; Marie-Elise Truchetet; Patrick Jego; Lorenzo Dagna; Jacob M. van Laar; Lidia Voigt; Susana Oliveira; Fabiola Atzeni; Masataka Kuwana; Arsene Mekinian; Mickaël Martin; Yoshiya Tanaka; Hidekata Yasuoka; Carmen-Pilar Simeón-Aznar; Tatsuya Atsumi; Magda Parvu; Ines Cordeiro; Nicoletta Del Papa; Thomas Karonitsch; Anna Bazela-Ostromecka; Enrico Selvi; Yasushi Kawaguchi; Tomas Soukup; Ignasi Rodriguez-Pinto; Marija Geroldinger-Simic; Gerard Espinosa; Karen Voigt; Torsten Kubacki; Olena Garmish; Marta Mosca; Ulrich Gerth; Ludmila Antonenko; Fabian A. Mendoza; Paolo Airò; Jeska de Vries-Bouwstra; Gabriela Riemekasten; Eric Hachulla; Andrea Doria; Edoardo Rosato; Nicolas Hunzelmann; Carlomaurizio Montecucco; Armando Gabrielli; Anna-Maria Hoffmann-Vold; Oliver Distler; Jennifer Ben Shimol; Maurizio Cutolo; Yannick Allanore; EUSTAR collaborators is a Medicine article available to read on EtoBox.
What is Cutaneous Manifestations, Clinical Characteristics, and Prognosis of Patients With Systemic Sclerosis Sine Scleroderma: Data From the International EUSTAR Database about?
## Importance Systemic sclerosis (SSc) sine scleroderma (ssSSc) is a subset of SSc defined by the absence of skin fibrosis. Little is known about the natural history and skin manifestations among patients with ssSSc. ## Objective To characterize the clinical phenotype of patients with ssSSc compared with patients with limited cutaneous SSc (lcSSc) and diffuse cutaneous SSc (dcSSc) within the EUSTAR database. ## Design, Setting, and Participants This longitudinal observational cohort study based on the international EUSTAR database included all patients fulfilling the classification criteria for SSc assessed by the modified Rodnan Skin score (mRSS) at inclusion and with at least 1 follow-up visit; ssSSc was defined by the absence of skin fibrosis (mRSS = 0 and no sclerodactyly) at all available visits. Data extraction was performed in November 2020, and data analysis was performed from April 2021 to April 2023. ## Main Outcomes and Measures Main outcomes were survival and skin manifestations (onset of skin fibrosis, digital ulcers, telangiectasias, puffy fingers). ## Results Among the 4263 patients fulfilling the inclusion criteria, 376 (8.8%) were classified as having ssSSc (mean [
Who reads Cutaneous Manifestations, Clinical Characteristics, and Prognosis of Patients With Systemic Sclerosis Sine Scleroderma: Data From the International EUSTAR Database?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Alain Lescoat; Suiyuan Huang; Patricia E. Carreira; Elise Siegert; Jeska de Vries-Bouwstra; Jörg H. W. Distler; Vanessa Smith; Francesco Del Galdo; Branimir Anic; Nemanja Damjanov; Simona Rednic; Camillo Ribi; Dominique Farge Bancel; Anna-Maria Hoffmann-Vold; Armando Gabrielli; Oliver Distler; Dinesh Khanna; Yannick Allanore; Marco Matucci Cerinic; Ulrich Walker; Florenzo Iannone; Radim Becvar; Otylia Kowal Bielecka; Carmen Pizzorni; Francesco Ciccia; Elise Siegert; Simona Rednic; Panayiotis G. Vlachoyiannopoulos; Jiri Stork; Murat Inanc; Patricia E. Carreira; Srdan Novak; László Czirják; Michele Iudici; Eugene J. Kucharz; Katja Perdan-Pirkmajer; Bernard Coleiro; Gianluca Moroncini; Dominique Farge Bancel; Roger Hesselstrand; Mislav Radic; Alexandra Balbir-Gurman; Andrea Lo Monaco; Raffaele Pellerito; Alessandro Giollo; Jadranka Morovic-Vergles; Christopher Denton; Madelon Vonk; Nemanja Damjanov; Jörg Henes; Vera Ortiz Santamaria; Stefan Heitmann; Dorota Krasowska; Paul Hasler; Michaela Kohm; Ivan Foeldvari; Gianluigi Bajocchi; Maria João Salvador; Bojana Stamenkovic; Carlo F. Selmi; Mohammed Tikly; Lidia P. Ananieva; Ariane Herrick; Ulf Müller-Ladner; Klaus Søndergaard; Francesco Puppo; Merete Engelhart; Gabriela Szücs; Carlos de la Puente; Valeria Riccieri; Ruxandra Maria Ionescu; Ami Sha; Ana Maria Gheorghiu; Cord Sunderkötter; Jörg Distler; Francesca Ingegnoli; Luc Mouthon; Vanessa Smith; Francesco Paolo Cantatore; Susanne Ullman; Carlos Alberto von Mühlen; Maria Rosa Pozzi; Kilian Eyerich; Piotr Wiland; Marie Vanthuyne; Juan Jose Alegre-Sancho; Kristine Herrmann; Ellen De Langhe; Branimir Anic; Marko Baresic; Miroslav Mayer; Maria Üprus; Kati Otsa; Sule Yavuz; Brigitte Granel; Carolina de Souza Müller; Svetlana Agachi; Simon Stebbings; Alessandro Mathieu; Alessandra Vacca; Percival D. Sampaio-Barros; Lisa Stamp; Kamal Solanki; Douglas Veale; Esthela Loyo; Carmen Tineo; Sergio Toloza; Mengtao Li; Walid Ahmed Abdel Atty Mohamed; Jacek Olas; Fahrettin Oksel; Figen Yargucu; Cristina-Mihaela Tanaseanu; Rosario Foti; Codrina Ancuta; Daniel E. Furst; Britta Maurer; Jacob van Laar; Marzena Olesinska; Cristiane Kayser; Nihal Fathi; Paloma García de la Peña Lefebvre; Jorge Juan Gonzalez Martin; Patrick Carpentier; Bernard Imbert; Camille Francès; Patricia Senet; Jean Sibilia; Ira Litinsky; Jean Luc Senécal; Martial Koenig; France Joval; Grodzicky Tamara; Francesco Del Galdo; Goda Seskute; Lesley Ann Saketkoo; Eduardo Kerzberg; Washington Bianchi; Breno Valdetaro Bianchi; Ivan Castellví; Jasminka Milas-Ahic; Roberta Visevic; Massimiliano Limonta; Doron Rimar; Maura Couto; François Spertini; Antonella Marcoccia; Sarah Kahl; Vivien M. Hsu; Thierry Martin; Sergey Moiseev; Pavel Novikov; Lorinda S. Chung; Tim Schmeiser; Dominik Majewski; Zbigniew Zdrojewski; Julia Martínez-Barrio; Dinesh Khanna; Vera Bernardino; Lelita Santo; Yair Levy; Elena Rezus; Omer Nuri Pamuk; Daniel Brito de Araujo; Piercarlo Sarzi Puttini; Marek Brzosko; Hadi Poormoghim; Marta Maman; Ina Kötter; Giovanna Cuomo; Francis Gaches; Laura Belloli; Petros Sfikakis; Juliana Markus; Daniel Furst; Ana-Maria Ramazan; Marie-Elise Truchetet; Patrick Jego; Lorenzo Dagna; Jacob M. van Laar; Lidia Voigt; Susana Oliveira; Fabiola Atzeni; Masataka Kuwana; Arsene Mekinian; Mickaël Martin; Yoshiya Tanaka; Hidekata Yasuoka; Carmen-Pilar Simeón-Aznar; Tatsuya Atsumi; Magda Parvu; Ines Cordeiro; Nicoletta Del Papa; Thomas Karonitsch; Anna Bazela-Ostromecka; Enrico Selvi; Yasushi Kawaguchi; Tomas Soukup; Ignasi Rodriguez-Pinto; Marija Geroldinger-Simic; Gerard Espinosa; Karen Voigt; Torsten Kubacki; Olena Garmish; Marta Mosca; Ulrich Gerth; Ludmila Antonenko; Fabian A. Mendoza; Paolo Airò; Jeska de Vries-Bouwstra; Gabriela Riemekasten; Eric Hachulla; Andrea Doria; Edoardo Rosato; Nicolas Hunzelmann; Carlomaurizio Montecucco; Armando Gabrielli; Anna-Maria Hoffmann-Vold; Oliver Distler; Jennifer Ben Shimol; Maurizio Cutolo; Yannick Allanore; EUSTAR collaborators
- Publisher
- American Medical Association (AMA)
- Published
- 2023
- Language
- EN
- Field
- Medicine (Health Sciences)