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Congenital Pelger-Huët anomaly in a Danish/Swedish Farmdog: Case Report by Janina Lukaszewska; Robin W Allison; Julita Stepkowska is a Agricultural and Biological Sciences article available to read on EtoBox.

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A 13 year old Danish/Swedish Farmdog from Denmark was evaluated in a veterinary clinic in Warsaw, Poland for evaluation of an orthopedic problem. Radiographs revealed spondylosis and degenerative vertebral disease, which responded to treatment with anti-inflammatory medications. A predominance of hyposegmented neutrophils and eosinophils containing condensed chromatin and normal cytoplasm were identified on a routine CBC. Follow-up blood film evaluations over the course of 12 months confirmed that the hyposegmented granulocytes persisted. The majority of neutrophils contained Grade 2 nuclei (slightly indented), and the mean nuclear score varied from 1.9 to 2.3. Pelger-Huët anomaly (PHA), presumably congenital, was diagnosed based on persistent hyposegmented granulocytes in the absence of an underlying cause for acquired PHA; genetically related dogs were unavailable for testing to confirm vertical transmission. To the authors' knowledge this is the first report of PHA in a Danish/Swedish Farmdog.

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Author

Janina Lukaszewska; Robin W Allison; Julita Stepkowska

Publisher

BioMed Central; Springer (Biomed Central Ltd.); [London]: BioMed Central; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 1751-0147)

Published

2011

Language

EN

Field

Agricultural and Biological Sciences (Life Sciences)