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Group Sequential Methods (Chapman & Hall CRC Interdisciplinary Statistics) by Christopher Jennison and Bruce W. Turnbull. is a nonfiction available to read on EtoBox.

What is Group Sequential Methods (Chapman & Hall CRC Interdisciplinary Statistics) about?

Group sequential methods answer the needs of clinical trial monitoring committees who must assess the data available at an interim analysis. These interim results may provide grounds for terminating the study-effectively reducing costs-or may benefit the general patient population by allowing early dissemination of its findings. Group sequential methods provide a means to balance the ethical and financial advantages of stopping a study early against the risk of an incorrect conclusion. Group Sequential Methods with Applications to Clinical Trials describes group sequential stopping rules designed to reduce average study length and control Type I and II error probabilities. The authors present one-sided and two-sided tests, introduce several families of group sequential tests, and explain how to choose the most appropriate test and interim analysis schedule. Their topics include placebo-controlled randomized trials, bio-equivalence testing, crossover and longitudinal studies, and linear and generalized linear models. Research in group sequential analysis has progressed rapidly over the past 20 years. Group Sequential Methods with Applications to Clinical Trials surveys and extends c

Who reads Group Sequential Methods (Chapman & Hall CRC Interdisciplinary Statistics)?

Author

Christopher Jennison and Bruce W. Turnbull.

Publisher

Chapman and Hall\/CRC

Published

1999

Language

EN

ISBN

9780367805326

Category

nonfiction

Subjects

Medical, Mathematics, Science