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What is Hackel Et Al in Vitro Activity of The Siderophore Cephalosporin Cefiderocol Against Carbapenem Nonsusceptible and about?

The study evaluates the in vitro activity of the siderophore cephalosporin, cefiderocol, against a global collection of multidrug-resistant Gram-negative bacilli from 2014 to 2016. Cefiderocol demonstrated potent activity, inhibiting 96.2% of tested isolates, with MIC90 values of 4 µg/ml for carbapenem-nonsusceptible Enterobacteriaceae and lower values for other resistant strains. These findings suggest cefiderocol as a promising option in treating infections caused by resistant Gram-negative bacteria.

Author

Mantcha Mantcha

Language

EN