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Does Image-guided Biopsy of Discitis-osteomyelitis Provide Meaningful Information to Impact Clinical Management? by Elisha Lim; William Walter; Soterios Gyftopoulos; Mohammad Samim is a Medicine article available to read on EtoBox.

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## Objective: The aims of this study are to assess the diagnostic yield of image-guided biopsy for discitis-osteomyelitis (do), identify factors associated with biopsy yield (laboratory, pre-defined mri findings, and biopsy technique), and impact of biopsy on management of patients appropriately selected according to the infectious disease society of america guidelines (idsa). ## Materials and methods: This is a retrospective review of patients who underwent biopsy for suspected do from 2011 to 2019. reference standards to establish diagnosis of do in order were histopathology/microbiology from biopsy or subsequent surgical sampling, positive blood culture or serology, and imaging/clinical follow-up. laboratory markers, pre-biopsy antibiotics and mri features, procedural-related variables, and impact of biopsy on management were assessed. multivariable logistic regression was also performed. ## Results: Out of 97 included patients, 78 were diagnosed with do. overall sensitivity of biopsy for detecting do was 41.0% (32/78), including 10 patients with positive histopathology only, 14 with positive biopsy culture only, and 8 with both. elevated esr (p < 0.001) and epidural collection

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Author

Elisha Lim; William Walter; Soterios Gyftopoulos; Mohammad Samim

Publisher

Springer; Springer-Verlag; Springer Verlag; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 0364-2348)

Published

2020

Language

EN

Field

Medicine (Health Sciences)