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What is Mechanisms of T Cell Cytotoxicity about?

This document discusses T-cell mediated cytotoxicity and the killing of infected cells. It describes: 1. CD8 cytotoxic T-lymphocytes (CTLs) kill intracellular pathogen-infected cells through direct contact with the infected cell. 2. The mechanism of CTL-mediated killing involves initial binding between the CTL and infected cell, formation of a conjugation, delivery of a lethal hit through lytic granules containing perforin and granzymes, detachment of the CTL, and death of the target cell. 3. CTLs use

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