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What is Understanding Autoimmunity and Disease about?

Autoimmunity refers to the presence of self-reactive antibodies or T cells, but does not always lead to autoimmune disease. Autoimmune diseases depend on genetic, viral, and hormonal factors and involve severe tissue damage. The key concepts are that recognition of autoantigens by lymphocytes is critical, tissue destruction requires both autoimmune cells and other factors, and autoimmune diseases almost always involve self-reactive CD4+ T cells inducing the condition. Breaking of self-tolerance can be cause

Author

Tasya Felicia Macellin

Language

EN