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Rhabdomyolysis in Older Adults: Outcomes and Prognostic Factors by Anne-Gaëlle Morin; Dominique Somme; Aline Corvol is a Medicine article available to read on EtoBox.

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## Background Rhabdomyolysis is a common condition in older adults, often associated with falls. However, prognostic factors for rhabdomyolysis have mainly been studied in middle-aged populations. ## Objective To test the hypothesis that age influences rhabdomyolysis prognostic factors. ## Methods This retrospective single-center observational study included all patients with a creatine kinase (CK) level greater than five times normal, admitted to Rennes University Hospital between 2013 and 2019. The primary endpoint was 30-day in-hospital mortality rate. ## Results 343 patients were included (median age: 75 years). The mean peak CK was 21,825 IU/L. Acute renal failure occurred in 57.7% of the cases. For patients aged 70 years and over, the main etiology was prolonged immobilization after a fall. The 30-day in-hospital mortality rate was 10.5% (23 deaths). The Charlson score, number of medications and CK and creatinine levels varied according to age. Multivariate analysis showed age to be a factor that was associated, although not proportionally, with 30-day in-hospital mortality. ## Conclusion Factors influencing rhabdomyolysis severity were not randomly distributed according to a

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Author

Anne-Gaëlle Morin; Dominique Somme; Aline Corvol

Publisher

BioMed Central

Published

2024

Language

EN

Field

Medicine (Health Sciences)