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Human Cytochrome P450 Enzymes Survey by Maryline Angelvin Firdaus is a document available to read on EtoBox.
What is Human Cytochrome P450 Enzymes Survey about?
The article surveys human oxidoreductases and cytochrome P450 enzymes involved in the metabolism of various chemicals, revealing that over 90% of metabolic reactions are catalyzed by P450 enzymes. Specifically, five P450 enzymes (1A2, 2C9, 2C19, 2D6, and 3A4) account for the majority of drug metabolism. The study emphasizes the dominant role of P450s in the metabolic activation of drugs and other chemicals, while also noting the minimal contributions from other oxidoreductases.
- Author
- Maryline Angelvin Firdaus
- Language
- EN