Opening book details…
Can I read Central Sleep Apnea: Pathophysiologic Classification on EtoBox?
Central Sleep Apnea: Pathophysiologic Classification by Shahrokh Javaheri; M Safwan Badr is a Psychology article available to read on EtoBox.
What is Central Sleep Apnea: Pathophysiologic Classification about?
## Abstract Central sleep apnea is not a single disorder; it can present as an isolated disorder or as a part of other clinical syndromes. In some conditions, such as heart failure, central apneic events are due to transient inhibition of ventilatory motor output during sleep, owing to the overlapping influences of sleep and hypocapnia. Specifically, the sleep state is associated with removal of wakefulness drive to breathe; thus, rendering ventilatory motor output dependent on the metabolic ventilatory control system, principally PaCO2. Accordingly, central apnea occurs when PaCO2 is reduced below the “apneic threshold”. Our understanding of the pathophysiology of central sleep apnea has evolved appreciably over the past decade; accordingly, in disorders such as heart failure, central apnea is viewed as a form of breathing instability, manifesting as recurrent cycles of apnea/hypopnea, alternating with hyperpnea. In other words, ventilatory control operates as a negative—feedback closed-loop system to maintain homeostasis of blood gas tensions within a relatively narrow physiologic range, principally PaCO2. Therefore, many authors have adopted the engineering concept of “loop gain
Who reads Central Sleep Apnea: Pathophysiologic Classification?
It is typically read by researchers, students, and practitioners in Psychology.
- Author
- Shahrokh Javaheri; M Safwan Badr
- Publisher
- Oxford University Press (OUP)
- Published
- 2022
- Language
- EN
- Field
- Psychology (Health Sciences)