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Late complement component deficiency and meningococcal disease: Clinical and immunological aspects by A.E. Platonov; C.A.P. Fijen; I.V. Vershinina; H. Kayhty; J. Dankert; E.J. Kuijper is a Immunology and Microbiology article available to read on EtoBox.

What is Late complement component deficiency and meningococcal disease: Clinical and immunological aspects about?

## Poster presentations hmmodej5ciencies 175 periods of exacerbation of the inflammatory process. Gram positive bacteria (mostly Staphylococcus aureus) are an important cause of bone infection. Neutrophils have been mcognised the most important micmbicidai cells fighting the infection. Rote of the immune system in limiting the spread of the infection is unclear. Some authors suggest disturbances in neutrophil functions responsible for long-lasting and recurrent symptoms of ChO. MaterY and Methods: We tested oxidative burst of spontaneous and PMA, fMLP and zymosan stimulated neuttophils in 16 patients suffering from ChO for 3 f 1.5 years. We measured in flow cytometry the percentage of platelets forming aggregates with neutrophils in whole blood. The patients were tested for erythrocyte sedimentation reaction, C reactive proteins, mucopmteins and immunogicbullns levels. 14 heatthy volunteers served as a control group. Oxidative burst of neutrophlls, expressed as lumind-enhanced chemiluminescence (CL) activity, was measured by means of 1251 Luminometer (Bio-Orbit, Turku, Finland). Percentage of platelet-neutrophil aggregates was tested using CDGI-FITC and CDlG-PE (Dacopatts a/s, Denm

Who reads Late complement component deficiency and meningococcal disease: Clinical and immunological aspects?

Author

A.E. Platonov; C.A.P. Fijen; I.V. Vershinina; H. Kayhty; J. Dankert; E.J. Kuijper

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0165-2478)

Published

1997

Language

EN

Field

Immunology and Microbiology (Life Sciences)