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Phloridzin: Biosynthesis, distribution and physiological relevance in plants by Christian Gosch; Heidi Halbwirth; Karl Stich is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is Phloridzin: Biosynthesis, distribution and physiological relevance in plants about?

The phenolic compound phloridzin (phloretin 2'-O-glucoside, phlorizin, phlorrhizin, phlorhizin or phlorizoside) is a prominent member of the chemical class of dihydrochalcones, which are phenylpropanoids. The apple tree (Malus sp.) accumulates high amounts of phloridzin, whereas few other species contain this compound only in low amounts. Additionally, Malus sp. show a species- and tissue-specific distribution of phloridzin and its derivatives. Whereas the physiological role of phloridzin in planta is not fully understood, the effect on human health - especially diabetes - and membrane permeability is well documented. The biosynthesis of phloridzin was investigated only recently with recombinant enzymes and plant protein extracts and involved a NADPH-dependent dehydrogenase, chalcone synthase and UDP-glucose:phloretin 2'-O-glycosyltransferase.

Who reads Phloridzin: Biosynthesis, distribution and physiological relevance in plants?

Author

Christian Gosch; Heidi Halbwirth; Karl Stich

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0031-9422)

Published

2010

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)