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Predictors of ovarian cancer survival: A population-based prospective study in Sweden by Ling Yang; Åsa Klint; Mats Lambe; Rino Bellocco; Tomas Riman; Kjell Bergfeldt; Ingemar Persson; Elisabete Weiderpass is a Medicine article available to read on EtoBox.
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## Abstract Ovarian cancer is the leading cause of death from gynecologic malignancies among women worldwide. Little is known about reproductive factors or lifestyle determinants and ovarian cancer prognosis. The objective of this study was to examine whether ovarian cancer survival is influenced by reproductive history, anthropometric characteristics, prediagnostic life‐style factors and family history of breast or ovarian cancer. The study population consisted of 635 epithelial ovarian cancer (EOC) cases derived from a nationwide population‐based case‐control study conducted in Sweden between 1993 and 1995. Exposure data on prediagnostic factors of interest were collected through questionnaires at the beginning of the parent study. Clinical data were abstracted from medical records. Cases were followed‐up by means of record linkage to nationwide registers until December 31, 2002. Cox proportional hazard regression model was used to estimate the prognostic effect of each factor in terms of hazard ratios (HR) and 95% confidence intervals (CI), following adjustment for age at diagnosis, FIGO tumor stage and WHO grade of tumor differentiation. Tumor characteristics significantly infl
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- Author
- Ling Yang; Åsa Klint; Mats Lambe; Rino Bellocco; Tomas Riman; Kjell Bergfeldt; Ingemar Persson; Elisabete Weiderpass
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; Research Square; Test accounts (ISSN 0020-7136)
- Published
- 2008
- Language
- EN
- Field
- Medicine (Health Sciences)