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Can I read Androgen and estrogen effect on guinea pig seminal vesicle muscle: A combined stereological and biochemical study on EtoBox?
Androgen and estrogen effect on guinea pig seminal vesicle muscle: A combined stereological and biochemical study by A. Bruengger; A. Mariotti; H. P. Rohr; W. Stahel; P. Wiederkehr; G. Bartsch; S. W. Carmichael; M. G. Mawhinney is a Medicine article available to read on EtoBox.
What is Androgen and estrogen effect on guinea pig seminal vesicle muscle: A combined stereological and biochemical study about?
A combined electron microscopic stereological and biochemical study of the smooth muscle cells of guinea pig seminal vesicles was performed in intact, castrated, castrated and dihydrotestosterone- or estradiol-treated adult animals. Castration led to cell atrophy as determined stereologically by a decreased single cell volume and biochemically by no change in DNA content coupled with an increase in the DNA concentration. Treatment of castrates with dihydrotestosterone restored both the stereological and biochemical parameters of the cell size to slightly supranormal levels. The estrogen-induced increase in muscle weight and DNA content appeared to be due only to hyperplasia of muscle cells and not to a proliferation of fibroblasts or to infiltration by inflammatory cells. In all treatment groups, including the estrogen-treated castrates, more than 95% of the cells in the tissue were smooth muscle cells, and there was no evidence that polyploidy contributed to changes in DNA levels. In addition, in the estrogen-treated muscles, DNA concentration remained high, and the stereologically determined cell size remained low. Therefore, both morphological and biochemical evidence indicate t
Who reads Androgen and estrogen effect on guinea pig seminal vesicle muscle: A combined stereological and biochemical study?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- A. Bruengger; A. Mariotti; H. P. Rohr; W. Stahel; P. Wiederkehr; G. Bartsch; S. W. Carmichael; M. G. Mawhinney
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0270-4137)
- Published
- 1985
- Language
- EN
- Field
- Medicine (Health Sciences)