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Changes in the GST activity of the mussel Mytilus galloprovincialis during exposure and depuration of microcystins by Sandra Fernandes; Martin Welker; Vitor Manuel Vasconcelos is a Environmental Science article available to read on EtoBox.

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## Abstract Mussels are quite resistant to cyanotoxins and their resistance may be because of an efficient metabolization of cyanotoxins by glutathione‐__S__‐transferases (GST) activity. Nevertheless, other secondary metabolites may interfere with the detoxication efficiency. The accumulation and depuration of hepatotoxins produced by the freshwater cyanobacterium __Microcystis aeruginosa__ in the mussel __Mytilus galloprovincialis__ were studied. Mussels were fed twice a day 1.5×10^5^ cells/mL of the toxic cyanobacterium, which produces microcystins (MCs) ‐FR, ‐LR and ‐WR, for 4 days. After that period, the animals were placed in toxin‐free water and were fed the green algae __Ankistrodesmus__ sp. During 2 weeks, the concentration of the toxin in the mussels was monitored using an ELISA assay. Mussels showed a maximum detectable level of MCs of 0.38 μg/g mussels dry weight (DW) during the accumulation period and 0.37 μg MC/g mussel DW by day 4 of the depuration period. Then there was a decrease trend with peaks of toxin at days 8 and 12 of the depuration period. The activity of the detoxication enzymes GST was studied and the results showed that the peaks of toxin in the mussels c

Who reads Changes in the GST activity of the mussel Mytilus galloprovincialis during exposure and depuration of microcystins?

Author

Sandra Fernandes; Martin Welker; Vitor Manuel Vasconcelos

Publisher

Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1932-5223)

Published

2009

Language

EN

Field

Environmental Science (Life Sciences)