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Can I read Interventions to Optimize Spinal Cord Perfusion in Patients With Acute Traumatic Spinal Cord Injury: An Updated Systematic Review on EtoBox?

Interventions to Optimize Spinal Cord Perfusion in Patients With Acute Traumatic Spinal Cord Injury: An Updated Systematic Review by Nathan Evaniew; Benjamin Davies; Farzin Farahbakhsh; Michael G. Fehlings; Mario Ganau; Daniel Graves; James D. Guest; Radha Korupolu; Allan R. Martin; Stephen L. McKenna; Lindsay A. Tetreault; Aditya Vedantam; Erika D. Brodt; Andrea C. Skelly; Brian K. Kwon is a Medicine article available to read on EtoBox.

What is Interventions to Optimize Spinal Cord Perfusion in Patients With Acute Traumatic Spinal Cord Injury: An Updated Systematic Review about?

## Study design Systematic review update. ## Objectives Interventions that aim to optimize spinal cord perfusion are thought to play an important role in minimizing secondary ischemic damage and improving outcomes in patients with acute traumatic spinal cord injuries (SCIs). However, exactly how to optimize spinal cord perfusion and enhance neurologic recovery remains controversial. We performed an update of a recent systematic review (Evaniew et al, J. Neurotrauma 2020) to evaluate the effects of Mean Arterial Pressure (MAP) support or Spinal Cord Perfusion Pressure (SCPP) support on neurological recovery and rates of adverse events among patients with acute traumatic SCI. ## Methods We searched PubMed/MEDLINE, EMBASE and ClinicalTrials.gov for new published reports. Two reviewers independently screened articles, extracted data, and evaluated risk of bias. We implemented the Grades of Recommendation, Assessment, Development, and Evaluation (GRADE) approach to rate confidence in the quality of the evidence. ## Results From 569 potentially relevant new citations since 2019, we identified 9 new studies for inclusion, which were combined with 19 studies from a prior review to give a t

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Author
Nathan Evaniew; Benjamin Davies; Farzin Farahbakhsh; Michael G. Fehlings; Mario Ganau; Daniel Graves; James D. Guest; Radha Korupolu; Allan R. Martin; Stephen L. McKenna; Lindsay A. Tetreault; Aditya Vedantam; Erika D. Brodt; Andrea C. Skelly; Brian K. Kwon
Publisher
SAGE Publications
Published
2024
Language
EN
Field
Medicine (Health Sciences)

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