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A new generation of high flex life polyurethane urea for polymer heart valve—Studies on in vivo biocompatibility and biodurability by Vinoy Thomas; Muthu Jayabalan is a Engineering article available to read on EtoBox.
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## Abstract Development of new generation high flex life polyurethane urea (HFL18‐PU) with appropriate elastic modulus, biocompatibility, blood compatibility, resistant to calcification, and biodurability for the long‐term use as cardiac device is still a challenge. This study reports the development of a fully aliphatic, ether‐free physically cross‐linked and low elastic modulus (6.841 ± 0.27 MPa) polyurethane urea having __in vivo__ biostability, __in vivo__ biocompatibility and high flex‐life (721 ± 30 million cycles) that can satisfy the requirements for the fabrication of tri‐leaflet heart valve. © 2008 Wiley Periodicals, Inc. J Biomed Mater Res, 2009
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- Author
- Vinoy Thomas; Muthu Jayabalan
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1549-3296)
- Published
- 2008
- Language
- EN
- Field
- Engineering (Physical Sciences)