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Are There Differences Between Intradermal and Intramuscular Injections of Botulinum Toxin on the Forehead? by Yu Jin Kim; Oh Kyung Lim; Won Jun Choi is a Medicine article available to read on EtoBox.

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## BACKGROUND The intradermal technique to inject botulinum toxin is a popular procedure in upper facial rejuvenation to minimize side effects, such as brow ptosis, and can sometimes result in a lifting effect. ## OBJECTIVE The present study investigated differences in effects according to injection modality. ## METHODS AND MATERIALS Fifteen women received intradermal injections of botulinum toxin (total dose, 8U) into the forehead, and 14 women received intramuscular injections. ## RESULTS The maximal antiwrinkle effect was recorded at Week 2, and the duration of the effect was the same in both groups. The brow position was lowered at Weeks 2 and 4 in the intramuscular injection group and was preserved in the intradermal injection group throughout the follow-up period. The amount of maximal voluntary eyebrow movement was decreased at Weeks 2 and 4 and recovered at Week 16 in both groups. The change in the electromyographic amplitude of the frontalis muscle was prolonged until Week 16 in both groups. Subjective satisfaction with wrinkles was similar in both groups. However, the intradermal injection was more painful. ## CONCLUSION Intradermal injection of botulinum toxin is a safe

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Author

Yu Jin Kim; Oh Kyung Lim; Won Jun Choi

Publisher

Ovid Technologies (Wolters Kluwer Health)

Published

2020

Language

EN

Field

Medicine (Health Sciences)