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Robot-assisted Versus Conventional Laparoscopic Radical Prostatectomy: A Systematic Review and Meta-analysis of Randomised Controlled Trials by Caelán Max Haney; Karl-Friedrich Kowalewski; Niklas Westhoff; Sigrun Holze; Enrico Checcuci; Manuel Neuberger; Henry Haapiainen; Luisa Egen; Kaipia Antti; Francesco Porpiglia; Jens-Uwe Stolzenburg is a Medicine article available to read on EtoBox.

What is Robot-assisted Versus Conventional Laparoscopic Radical Prostatectomy: A Systematic Review and Meta-analysis of Randomised Controlled Trials about?

Context: Robot-assisted radical prostatectomy (RARP) has largely replaced conventional laparoscopic radical prostatectomy (LRP) even though the costs are significantly higher. Justification for this change is the hope for better postoperative functional results because of better dissection of the neurovascular bundle. Objective: To perform a systematic review and meta-analysis of randomised controlled trials (RCTs) comparing RARP and LRP for the primary outcome of continence (use of 0 pads or 1 safety pad) at 12 mo after surgery. Evidence acquisition: We searched the CENTRAL, MEDLINE, and Web of Science databases for RCTs comparing RARP versus LRP for adults with localised prostate cancer (PC). Where possible, individual-patient data were obtained. Secondary outcomes were potency for patients potent at baseline; a trifecta of patients continent and potent and no recurrence/further treatment; positive surgical margins; biochemical recurrence; and further treatment for PC. The systematic review was registered prospectively (reviewregistry1190 on www.researchregistry.com/). Evidence synthesis: Five RCTs were identified. Three trial teams provided data. For another trial, only publishe

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Author

Caelán Max Haney; Karl-Friedrich Kowalewski; Niklas Westhoff; Sigrun Holze; Enrico Checcuci; Manuel Neuberger; Henry Haapiainen; Luisa Egen; Kaipia Antti; Francesco Porpiglia; Jens-Uwe Stolzenburg

Publisher

Elsevier BV

Published

2023

Language

EN

Field

Medicine (Health Sciences)