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Can I read Microbial Enantioselective Reduction of Ethyl-2-oxo-4-phenyl-butanoate on EtoBox?
Microbial Enantioselective Reduction of Ethyl-2-oxo-4-phenyl-butanoate by Paulo S. Bergo de Lacerda; Joyce Benzaquem Ribeiro; Selma G.F. Leite; Ricardo B. Coelho; Edson Luiz da Silva Lima; O.A.C. Antunes is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Microbial Enantioselective Reduction of Ethyl-2-oxo-4-phenyl-butanoate about?
Different microorganisms (MOs) were used to carry out the enantioselective reduction of ethyl-2-oxo-4-phenylbutanoate to (S)-(+)-2-hydroxy-4-phenylbutanoate or (R)-(+)-2-hydroxy-4-phenylbutanoate. Commercially available Saccharomyces cerevisiae and Dekera sp. led to over 92% ee of (S)-(+)-2-hydroxy-4-phenylbutanoate. Kluyveromyces marxianus gave the opposite isomer with 32% ee (R). All reactions, except those with Hansenula sp., proceeded to greater than 90% conversion. This the first report on the use of Dekera sp., Hansenula sp. and K. marxianus in the reduction of ␣-ketoesters.
Who reads Microbial Enantioselective Reduction of Ethyl-2-oxo-4-phenyl-butanoate?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Paulo S. Bergo de Lacerda; Joyce Benzaquem Ribeiro; Selma G.F. Leite; Ricardo B. Coelho; Edson Luiz da Silva Lima; O.A.C. Antunes
- Publisher
- Elsevier Science; Elsevier ; Elsevier BV (ISSN 1369-703X)
- Published
- 2006
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Physical Sciences)