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Can I read The Effect of Neural Stem Cells Transplantation on the Protection of Retinal Ganglion Cells of Sprague‐dawly Rats with Optic Nerve Injury on EtoBox?
The Effect of Neural Stem Cells Transplantation on the Protection of Retinal Ganglion Cells of Sprague‐dawly Rats with Optic Nerve Injury by Hao Ran Liu; Yi Mou Zhang; Tong Cheng Liu; Chang Hong Yang; Feng Hua Cheng; Jing Fang Liu; Fang Fang; Jia Sheng Fang is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is The Effect of Neural Stem Cells Transplantation on the Protection of Retinal Ganglion Cells of Sprague‐dawly Rats with Optic Nerve Injury about?
Stem cell therapy sheds light on the cure of ischemic heart infarct. One of the key issues is to establish an adult stem cell line, which has high potent proliferation and cardiac differentiation. We have screened a novel clonogenic cells (AMCSCs) from adult rat bone marrow, which is negative for CD4, CD10, CD13, CD31, CD34, CD45, CD85, CD102, ICAM, VCAM, c-kit and Flk-1. The results suggest that AMCSC was not heamotopoietic stem cells, mesenchymal stem cells or endothelial progenitors, but a novel clone of adult stem cell. AMCSCs possessed strong potent to proliferation and could grow consecutively for 220 passages. After being treated with differentiation medium, cardiac differentiation and smooth muscle differentiation could be induced in AMCSCs.. The b-galactosidase staining for AMCSCs from the 22 nd , 52 nd , 104 th , 129 th , and 184 th passages indicated that AMCSCs were negative for the aging marker b-galactosidase. In addition, after being cultured under low-serum condition, the proliferation capacity of AMCSCs declined. Furthermore, AMCSCs did not develop into tumors after being injected into nude mice. Our results suggest that AMCSCs could be a novel clone of adult stem
Who reads The Effect of Neural Stem Cells Transplantation on the Protection of Retinal Ganglion Cells of Sprague‐dawly Rats with Optic Nerve Injury?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Hao Ran Liu; Yi Mou Zhang; Tong Cheng Liu; Chang Hong Yang; Feng Hua Cheng; Jing Fang Liu; Fang Fang; Jia Sheng Fang
- Publisher
- Elsevier Science; Wiley (John Wiley & Sons); Wiley-Blackwell; Wiley (ISSN 1065-6995)
- Published
- 2008
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)