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Optimization of growth conditions for the biosynthesis of medium-chain length polyhydroxyalkanoates from Bacillus megaterium DSM 509: experimental analysis, statistical modelling, and characterization by Salma Shahid; David Corroler; Ridha Mosrati; Caroline Amiel; Jean-Luc Guillard; Sadia Noreen; Sofia Parveen; Muhammad Bilal is a Health Professions article available to read on EtoBox.
What is Optimization of growth conditions for the biosynthesis of medium-chain length polyhydroxyalkanoates from Bacillus megaterium DSM 509: experimental analysis, statistical modelling, and characterization about?
Bioplastics are biobased materials produced from renewable sources like vegetable fats and oils, corn starch, straw, woodchips, sawdust, and recycled food wastes. Microbial polyhydroxyalkanoate (PHA), a type of bioplastics, has unique biocompatibility, non-toxicity, and biodegradability properties, making it suitable as an eco-friendly plastic material. Bacillus megaterium DSM 509 is known to produce short-chain length (scl) PHA. The present study explores the capability of Bacillus megaterium DSM 509 to produce a novel type of PHA, medium-chain length (mcl), and its mixture with scl-PHA. Statistical modelling and experimental results were used to optimize the growth conditions for enhanced production of cost-effective and biocompatible polyhydroxyoctanoates and polyhydroxydecanoates. A 6-run mixture design for glycerol and ammonium sulphate concentrations ratio was performed. A linear regression model was built based on experimental data, and the optimum conditions for different glycerol and nitrogen concentrations were derived and validated. A positive correlation (r2, 0.95, and 0.87) was observed, resulting in the model's fitness. Optical density studies showed the impact of dis
Who reads Optimization of growth conditions for the biosynthesis of medium-chain length polyhydroxyalkanoates from Bacillus megaterium DSM 509: experimental analysis, statistical modelling, and characterization?
It is typically read by researchers, students, and practitioners in Health Professions.
- Author
- Salma Shahid; David Corroler; Ridha Mosrati; Caroline Amiel; Jean-Luc Guillard; Sadia Noreen; Sofia Parveen; Muhammad Bilal
- Publisher
- Springer Science and Business Media LLC
- Published
- 1987
- Language
- EN
- Field
- Health Professions (Health Sciences)